The Tridion template builder is a great tool, but it can sometimes be tricky to install. SDL have chosen to distribute it through the ClickOnce mechanism (see https://en.wikipedia.org/wiki/ClickOnce). This does not work with Chrome out of the box, and I haven’t always had good results with the various ClickOnce Chrome extensions out there. Instead, I normally start up IE and point it to the CM site, click on the Tools ribbon and install the Template Builder from there.
There are times when even this approach does not work, for example if I’m working on some locked down machine. For these occasions it is good to know that the Template Builder is portable – or rather portable-ish.